Searchable abstracts of presentations at key conferences in endocrinology

ea0063pl7 | Control of Integrative Physiology by the Melanocortin Circuitry | ECE2019

Control of Integrative Physiology by the Melanocortin Circuitry

Bruning Mr. Jens Claus

Proopiomelanocortin (POMC)- and agouti related peptide (AgRP)-expressing neurons in the arcuate nucleus of the hypothalamus (ARH) are critical regulators of food intake and energy homeostasis. They rapidly integrate the energy state of the organism through sensing fuel availability via hormones, nutrient components and even rapidly upon sensory food perception. Importantly, they not only regulate feeding responses, but numerous autonomic responses including glucose and lipid m...